RHBDD1 Antikörper

Produktnummer ABIN7118505

Dieses Anti-RHBDD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RHBDD1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für RHBDD1 Antikörper (ABIN7118505)

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHBDD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RHBDD1 Antikörper

Verwendungszweck: RHBDD1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: rhomboid domain containing 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RHBDD1

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Andere Bezeichnung: RHBDD1

Hintergrund:

Synonyms: Rhomboid-related protein 4 (RRP4)|Rhomboid domain-containing protein 1|Rhomboid-like protein 4|RHBDD1|RHBDL4

Background: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation(ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum(ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.

Molekulargewicht: 36 kDa

Gen-ID: 84236

UniProt: Q8TEB9