ARHGEF18 Antikörper

Produktnummer ABIN7118503

Produktdetails anti-ARHGEF18 Antikörper

Target: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF18 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: rho/rac guanine nucleotide exchange factor(GEF) 18

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ARHGEF18

Target: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Andere Bezeichnung: ARHGEF18 (ARHGEF18 Produkte)

Synonyme: arhgef18 antikoerper, wu:fc21e04 antikoerper, wu:fj05f11 antikoerper, zgc:85686 antikoerper, P114-RhoGEF antikoerper, AI467246 antikoerper, D030053O22Rik antikoerper, rho/rac guanine nucleotide exchange factor (GEF) 18a antikoerper, Rho/Rac guanine nucleotide exchange factor (GEF) 18 antikoerper, Rho/Rac guanine nucleotide exchange factor 18 antikoerper, rho guanine nucleotide exchange factor 18 antikoerper, rho/rac guanine nucleotide exchange factor (GEF) 18 antikoerper, arhgef18a antikoerper, ARHGEF18 antikoerper, LOC100027283 antikoerper, Arhgef18 antikoerper

Hintergrund: Synonyms:KIAA0521 Background:Acts as guanine nucleotide exchange factor(GEF) for RhoA GTPases. Its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species(ROS). Does not act as a GEF for CDC42. The G protein beta-gamma(Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production. Required for EPB41L4B-mediated regulation of the circumferential actomyosin belt in epithelial cells(PubMed:22006950).

Molekulargewicht: 120-130 kDa

Gen-ID: 23370

UniProt: Q6ZSZ5

Pathways: Neurotrophin Signalübertragung