Der Kaninchen Polyklonal Anti-RGS7-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, RGS7 in Proben von Human, Maus und Ratte zu detektieren.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
RGS7
(Regulator of G-Protein Signaling 7 (RGS7))
Andere Bezeichnung
RGS7
Hintergrund
Synonyms: Background:Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity(PubMed:10521509). May play a role in synaptic vesicle exocytosis(PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling(PubMed:15897264).