RQCD1 Antikörper

Produktnummer ABIN7118331

Der Kaninchen Polyklonal anti-RQCD1 Antikörper (ABIN7118331) detektiert spezifisch RQCD1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RQCD1 Antikörper (ABIN7118331)

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RQCD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RQCD1 Antikörper

Verwendungszweck: CNOT9 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RCD1 required for cell differentiation1 homolog(S. pombe)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RQCD1

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Andere Bezeichnung: CNOT9

Hintergrund:

Synonyms: CCR4-NOT transcription complex subunit 9|Cell differentiation protein RQCD1 homolog (Rcd-1)|CNOT9|RCD1|RQCD1

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB-and JUN-dependent transcription. May play a role in cell differentiation(By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T(in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

Molekulargewicht: 30-40 kDa

Gen-ID: 9125

UniProt: Q92600

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling