RRAGB Antikörper
Kurzübersicht für RRAGB Antikörper (ABIN7118323)
Target
Alle RRAGB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- RRAGB antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- Ras-related GTP binding B
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- RRAGB (Ras-Related GTP Binding B (RRAGB))
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Andere Bezeichnung
- RRAGB
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Hintergrund
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Synonyms: Ras-related GTP-binding protein B (Rag B, RagB)|RRAGB
Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
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Molekulargewicht
- 40 kDa
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Gen-ID
- 10325
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UniProt
- Q5VZM2
Target
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