RSPO2 Antikörper (AA 22-243)
Kurzübersicht für RSPO2 Antikörper (AA 22-243) (ABIN7118172)
Target
Alle RSPO2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 22-243
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Verwendungszweck
- RSPO2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 22-243aa
Immunogen: R-spondin 2 homolog
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000, IP: 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- RSPO2 (R-Spondin 2 (RSPO2))
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Andere Bezeichnung
- RSPO2
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Hintergrund
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Synonyms: R-spondin-2|Roof plate-specific spondin-2 (hRspo2)|RSPO2
Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
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Molekulargewicht
- 33 kDa
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Gen-ID
- 340419
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UniProt
- Q6UXX9
Target
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