PTPMT1 Antikörper

Produktnummer ABIN7118052

Dieses Anti-PTPMT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PTPMT1 in ELISA, WB und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PTPMT1 Antikörper (ABIN7118052)

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPMT1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PTPMT1 Antikörper

Verwendungszweck: PTPMT1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: protein tyrosine phosphatase, mitochondrial 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Andere Bezeichnung: PTPMT1

Hintergrund:

Synonyms: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1|PTEN-like phosphatase|Phosphoinositide lipid phosphatase|Protein-tyrosine phosphatase mitochondrial 1|PTPMT1|MOSP|PLIP

Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity).

Molekulargewicht: 21-23 kDa

Gen-ID: 114971

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process