POFUT1 Antikörper
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- Target Alle POFUT1 Antikörper anzeigen
- POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POFUT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- protein O-fucosyltransferase 1
- Isotyp
- IgG
- Top Product
- Discover our top product POFUT1 Primärantikörper
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anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 238-388) antibody
POFUT1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 1-194) antibodyPOFUT1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 243-393) antibodyPOFUT1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) antibodyPOFUT1 Reaktivität: Human, Maus, Ratte IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 344-373), (C-Term) antibodyPOFUT1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB32435 unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 85-194) antibodyPOFUT1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3H1 unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (C-Term) antibodyPOFUT1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (C-Term) antibodyPOFUT1 Reaktivität: Human, Hund, Affe, Schwein WB, IHC, IP, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (N-Term) antibodyPOFUT1 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Protein O-Fucosyltransferase 1 (POFUT1) (AA 101-150) antibodyPOFUT1 Reaktivität: Human, Maus, Ratte, Hund, Affe, Schwein, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))
- Andere Bezeichnung
- POFUT1 (POFUT1 Produkte)
- Hintergrund
- Synonyms:FUT12, KIAA0180 Background:Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP-fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that can then extend the fucosylation on the NOTCH EGF repeats. This extended fucosylation is required for optimal ligand binding and canonical NOTCH signaling induced by DLL1 or JAGGED1. Fucosylates AGRN and determines its ability to cluster acetylcholine receptors(AChRs).
- Molekulargewicht
- 44 kDa
- Gen-ID
- 23509
- UniProt
- Q9H488
- Pathways
- Notch Signalweg, SARS-CoV-2 Protein Interaktom
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