PRMT5 Antikörper (AA 76-291)

Produktnummer ABIN7117928

Der Kaninchen Polyklonal Anti-PRMT5-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, PRMT5 in Proben von Human, Maus, Ratte und Affe zu detektieren.

Kurzübersicht für PRMT5 Antikörper (AA 76-291) (ABIN7117928)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PRMT5 Antikörper

Bindungsspezifität: AA 76-291

Verwendungszweck: PRMT5 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 76-291aa

Immunogen: protein arginine methyltransferase 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Andere Bezeichnung: PRMT5

Hintergrund:

Synonyms: Protein arginine N-methyltransferase 5 (PRMT5)|72 kDa ICln-binding protein|Histone-arginine N-methyltransferase PRMT5|Jak-binding protein 1|Shk1 kinase-binding protein 1 homolog (SKB1 homolog, SKB1Hs)|Protein arginine N-methyltransferase 5, N-terminally processed|PRMT5|HRMT1L5|IBP72|JBP1|SKB1

Background: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 70 kDa

Gen-ID: 10419

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development