Der Kaninchen Polyklonal Anti-PRELID1-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, PRELID1 in Proben von Human, Maus und Ratte zu detektieren.
PRELID1
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
IHC: 1:20-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
PRELID1
(PRELI Domain Containing 1 (PRELID1))
Andere Bezeichnung
PRELID1
Hintergrund
Synonyms:CGI 106, PRELI, PRELI domain containing 1, PRELID1, PX19, Px19 like protein, SBBI12 Background:Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.