PQBP1 Antikörper
Kurzübersicht für PQBP1 Antikörper (ABIN7117652)
Target
Alle PQBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- PQBP1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- polyglutamine binding protein 1
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Isotyp
- IgG
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anti-Polyglutamine Binding Protein 1 (PQBP1) antibody
PQBP1 Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 184-265) antibodyPQBP1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1A11 unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 1-265) antibodyPQBP1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3H7 unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 1-265) antibodyPQBP1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 184-265) antibodyPQBP1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 58-107) antibodyPQBP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Affe, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 2-265) antibodyPQBP1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) antibodyPQBP1 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) (AA 72-121) antibodyPQBP1 Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Polyglutamine Binding Protein 1 (PQBP1) antibodyPQBP1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
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Andere Bezeichnung
- PQBP1
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Hintergrund
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Synonyms: Polyglutamine-binding protein 1 (PQBP-1)|38 kDa nuclear protein containing a WW domain (Npw38)|Polyglutamine tract-binding protein 1|PQBP1|NPW38
Background: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
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Molekulargewicht
- 38 kDa, 30 kDa
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Gen-ID
- 10084
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UniProt
- O60828
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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