PLCD4 Antikörper
Kurzübersicht für PLCD4 Antikörper (ABIN7117488)
Target
Alle PLCD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- PLCD4 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- phospholipase C, delta 4
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Isotyp
- IgG
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Applikationshinweise
- IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- PLCD4 (Phospholipase C, delta 4 (PLCD4))
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Andere Bezeichnung
- PLCD4
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Hintergrund
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Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4)|Phosphoinositide phospholipase C-delta-4|Phospholipase C-delta-4 (PLC-delta-4)|PLCD4
Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
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Gen-ID
- 84812
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UniProt
- Q9BRC7
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Pathways
- Inositol Metabolic Process
Target
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