PDZK1 Antikörper

Produktnummer ABIN7117270

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDZK1 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PDZK1 Antikörper (ABIN7117270)

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PDZK1 Antikörper

Verwendungszweck: PDZK1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: PDZ domain containing 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:20 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PDZK1

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Andere Bezeichnung: PDZK1

Hintergrund:

Synonyms: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3)|CFTR-associated protein of 70 kDa|Na(+)/H(+) exchanger regulatory factor 3|Na/Pi cotransporter C-terminal-associated protein 1 (NaPi-Cap1)|PDZ domain-containing protein 1|Sodium-hydrogen exchanger regulatory factor 3|PDZK1|CAP70|NHERF3|PDZD1

Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 67 kDa

Gen-ID: 5174

UniProt: Q5T2W1