TENT4B (AA 400-465) Antikörper

Produktnummer ABIN7117222

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in ELISA, IP und WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für TENT4B (AA 400-465) Antikörper (ABIN7117222)

Target: TENT4B

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: ELISA, Immunoprecipitation (IP), Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 400-465

Verwendungszweck: TENT4B antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 400-465aa

Immunogen: PAP associated domain containing 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: TENT4B

Hintergrund:

Synonyms: Terminal nucleotidyltransferase 4B|Non-canonical poly(A) RNA polymerase PAPD5|PAP-associated domain-containing protein 5|Terminal guanylyltransferase|Terminal uridylyltransferase 3 (TUTase 3)|Topoisomerase-related function protein 4-2 (TRF4-2)|TENT4B|GLD4|PAPD5|TRF4-2|TUT3

Background: Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

Molekulargewicht: 50 kDa, 80 kDa

Gen-ID: 64282

UniProt: Q8NDF8