PAK1IP1 Antikörper

Produktnummer ABIN7117207

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAK1IP1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PAK1IP1 Antikörper (ABIN7117207)

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK1IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PAK1IP1 Antikörper

Verwendungszweck: PAK1IP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: PAK1 interacting protein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PAK1IP1

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Andere Bezeichnung: PAK1IP1

Hintergrund:

Synonyms: p21-activated protein kinase-interacting protein 1|PAK/PLC-interacting protein 1 (hPIP1)|PAK1-interacting protein 1|WD repeat-containing protein 84|PAK1IP1|PIP1|WDR84

Background: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.

Molekulargewicht: 44 kDa

Gen-ID: 55003

UniProt: Q9NWT1

Pathways: Telomere Maintenance