SLCO4C1 Antikörper

Produktnummer ABIN7117131

Dieses Anti-SLCO4C1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SLCO4C1 in WB, ELISA und IHC. Geeignet für Human und Maus.

Kurzübersicht für SLCO4C1 Antikörper (ABIN7117131)

Target: SLCO4C1 (OATP-H) (Organic Anion Transporter H (OATP-H))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLCO4C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SLCO4C1 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: solute carrier organic anion transporter family, member 4C1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SLCO4C1

Target: SLCO4C1 (OATP-H) (Organic Anion Transporter H (OATP-H))

Andere Bezeichnung: SLCO4C1

Hintergrund: Synonyms:OATP H, OATP M1, OATP4C1, OATPX, Organic anion transporter M1, PRO2176, SLC21A20, SLCO4C1 Background:Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.

Molekulargewicht: 80 kDa

Gen-ID: 227394

UniProt: Q8BGD4