NUF2 Antikörper
Kurzübersicht für NUF2 Antikörper (ABIN7117086)
Target
Alle NUF2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NUF2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- NUF2, NDC80 kinetochore complex component, homolog
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))
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Andere Bezeichnung
- NUF2
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Hintergrund
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Synonyms: Kinetochore protein Nuf2 (hNuf2, hNuf2R, hsNuf2)|Cell division cycle-associated protein 1|NUF2|CDCA1|NUF2R
Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).
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Molekulargewicht
- 50 kDa
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Gen-ID
- 83540
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UniProt
- Q9BZD4
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Pathways
- Maintenance of Protein Location
Target
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