NMNAT3 Antikörper
Kurzübersicht für NMNAT3 Antikörper (ABIN7116866)
Target
Alle NMNAT3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NMNAT3 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- nicotinamide nucleotide adenylyltransferase 3
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
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Andere Bezeichnung
- NMNAT3
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Hintergrund
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Synonyms: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3)|Nicotinamide-nucleotide adenylyltransferase 3 (NMN adenylyltransferase 3)|Nicotinate-nucleotide adenylyltransferase 3 (NaMN adenylyltransferase 3)|Pyridine nucleotide adenylyltransferase 3 (PNAT-3)|NMNAT3
Background: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide(NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide(NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate(TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate(NHD), nicotinamide guanine dinucleotide(NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury.
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Molekulargewicht
- 24-28 kDa
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Gen-ID
- 349565
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UniProt
- Q96T66
Target
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