NHP2 Antikörper
Kurzübersicht für NHP2 Antikörper (ABIN7116860)
Target
Alle NHP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NHP2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- NHP2 ribonucleoprotein homolog
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- NHP2 (NHP2 Ribonucleoprotein (NHP2))
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Andere Bezeichnung
- NHP2
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Hintergrund
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Synonyms: H/ACA ribonucleoprotein complex subunit 2|Nucleolar protein family A member 2|snoRNP protein NHP2|NHP2|NOLA2
Background: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein(H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme.
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Molekulargewicht
- 17-20 kDa
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Gen-ID
- 55651
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UniProt
- Q9NX24
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Pathways
- Telomere Maintenance
Target
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