MX1 Antikörper

Produktnummer ABIN7116666

Dieses Anti-MX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MX1 in WB, IHC, ELISA, IP und IF. Geeignet für Human und Maus.

Kurzübersicht für MX1 Antikörper (ABIN7116666)

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-MX1 Antikörper

Verwendungszweck: MX1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Myxovirus resistance protein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Andere Bezeichnung: MX1

Hintergrund:

Synonyms: Interferon-induced GTP-binding protein Mx1|Interferon-induced protein p78 (IFI-78K)|Interferon-regulated resistance GTP-binding protein MxA|Myxoma resistance protein 1|Myxovirus resistance protein 1|Interferon-induced GTP-binding protein Mx1, N-terminally processed|MX1

Background: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Molekulargewicht: 76 kDa

Gen-ID: 4599

UniProt: P20591