MLXIP Antikörper

Produktnummer ABIN7116474

Dieser Anti-MLXIP-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von MLXIP in ELISA, WB, IHC und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MLXIP Antikörper (ABIN7116474)

Target: MLXIP (MLX Interacting Protein (MLXIP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLXIP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MLXIP Antikörper

Verwendungszweck: MLXIP antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: MLX interacting protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MLXIP

Target: MLXIP (MLX Interacting Protein (MLXIP))

Andere Bezeichnung: MLXIP

Hintergrund:

Synonyms: MLX-interacting protein|Class E basic helix-loop-helix protein 36 (bHLHe36)|Transcriptional activator MondoA|MLXIP|BHLHE36|KIAA0867|MIR|MONDOA

Background: Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

Molekulargewicht: 130 kDa

Gen-ID: 22877

UniProt: Q9HAP2