C20orf72 Antikörper
Kurzübersicht für C20orf72 Antikörper (ABIN7116334)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- MGME1 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- chromosome 20 open reading frame 72
-
Isotyp
- IgG
-
-
anti-Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) (AA 81-260) antibody
MGME1 Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
-
Andere Bezeichnung
- MGME1
-
Hintergrund
-
Synonyms: Mitochondrial genome maintenance exonuclease 1|MGME1|C20orf72|DDK1
Background: Metal-dependent single-stranded DNA(ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA(mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine(5hmC)-containing DNA in stem cells.
-
Molekulargewicht
- 36-39 kDa
-
Gen-ID
- 92667
-
UniProt
- Q9BQP7
Target
-
