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MCM8 Antikörper

Dieses Anti-MCM8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MCM8 in WB und ELISA. Geeignet für Human, Ratte und Maus.
Produktnummer ABIN7116318

Kurzübersicht für MCM8 Antikörper (ABIN7116318)

Target

Alle MCM8 Antikörper anzeigen
MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reaktivität

  • 36
  • 10
  • 10
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human, Ratte, Maus

Wirt

  • 35
  • 1
Kaninchen

Klonalität

  • 35
  • 1
Polyklonal

Konjugat

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MCM8 Antikörper ist unkonjugiert

Applikation

  • 25
  • 17
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    minichromosome maintenance complex component 8

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

    Andere Bezeichnung

    MCM8

    Hintergrund

    Synonyms:C20orf154 Background:Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex(pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex(ORC). Binds chromatin throughout the cell cycle.

    Molekulargewicht

    95 kDa

    Gen-ID

    84515

    UniProt

    Q9UJA3

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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