MICAL1 Antikörper

Produktnummer ABIN7116285

Der Kaninchen Polyklonal anti-MICAL1 Antikörper (ABIN7116285) detektiert spezifisch MICAL1 in WB, FACS, IHC, ELISA und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für MICAL1 Antikörper (ABIN7116285)

Target: MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MICAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-MICAL1 Antikörper

Verwendungszweck: MICAL1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: microtubule associated monoxygenase, calponin and LIM domain containing 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MICAL1

Target: MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))

Andere Bezeichnung: MICAL1

Hintergrund:

Synonyms: [F-actin]-monooxygenase MICAL1|Molecule interacting with CasL protein 1 (MICAL-1)|NEDD9-interacting protein with calponin homology and LIM domains|MICAL1|MICAL|NICAL

Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4.

Molekulargewicht: 120 kDa

Gen-ID: 64780

UniProt: Q8TDZ2