METAP2 Antikörper
Kurzübersicht für METAP2 Antikörper (ABIN7116239)
Target
Alle METAP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- METAP2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- methionyl aminopeptidase 2
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Isotyp
- IgG
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anti-Methionyl Aminopeptidase 2 (METAP2) (AA 2-212) antibody
METAP2 Reaktivität: Human WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 1F6 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyKD Validated METAP2 Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 23GB2565 unconjugated Recombinant Antibody
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 313-449) antibodyMETAP2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-478) antibodyMETAP2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 437-467), (C-Term) antibodyMETAP2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4959-4960 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 95-144) antibodyMETAP2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Affe, Fledermaus, Hamster, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-220) antibodyMETAP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Monoclonal 8F2 unconjugated Recombinant Antibody
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 10-40), (N-Term) antibodyMETAP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB5103 unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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Andere Bezeichnung
- METAP2
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Hintergrund
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Synonyms: Methionine aminopeptidase 2 (MAP 2, MetAP 2)|Initiation factor 2-associated 67 kDa glycoprotein (p67, p67eIF2)|Peptidase M|METAP2|MNPEP|P67EIF2
Background: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged(Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
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Molekulargewicht
- 67 kDa
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Gen-ID
- 10988
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UniProt
- P50579
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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