MED17 Antikörper

Produktnummer ABIN7116122

Der Kaninchen-Polyklonal Anti-MED17-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von MED17 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für MED17 Antikörper (ABIN7116122)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MED17 Antikörper

Verwendungszweck: MED17 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: mediator complex subunit 17

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Andere Bezeichnung: MED17

Hintergrund:

Synonyms: Mediator of RNA polymerase II transcription subunit 17|Activator-recruited cofactor 77 kDa component (ARC77)|Cofactor required for Sp1 transcriptional activation subunit 6 (CRSP complex subunit 6)|Mediator complex subunit 17|Thyroid hormone receptor-associated protein complex 80 kDa component (Trap80)|Transcriptional coactivator CRSP77|Vitamin D3 receptor-interacting protein complex 80 kDa component (DRIP80)|MED17|ARC77|CRSP6|DRIP77|DRIP80|TRAP80

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Molekulargewicht: 80 kDa

Gen-ID: 9440

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha