LOXL1 Antikörper

Produktnummer ABIN7115988

Dieses Anti-LOXL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LOXL1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für LOXL1 Antikörper (ABIN7115988)

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LOXL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LOXL1 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: lysyl oxidase-like 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Andere Bezeichnung: LOXL1

Hintergrund: Synonyms:LOL, LOXL, LOXL1, Lysyl oxidase homolog 1, lysyl oxidase like 1, Lysyl oxidase like protein 1 Background:This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Molekulargewicht: 70kDa

Gen-ID: 4016

UniProt: Q08397