LNX1 Antikörper
Kurzübersicht für LNX1 Antikörper (ABIN7115860)
Target
Alle LNX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- LNX1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ligand of numb-protein X 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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Andere Bezeichnung
- LNX1
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Hintergrund
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Synonyms: E3 ubiquitin-protein ligase LNX|Ligand of Numb-protein X 1|Numb-binding protein 1|PDZ domain-containing RING finger protein 2|RING-type E3 ubiquitin transferase LNX|LNX1|LNX|PDZRN2
Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 84708
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UniProt
- Q8TBB1
Target
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