Dieses Anti-LGR6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LGR6 in WB, ELISA, IHC und FACS. Geeignet für Human, Maus und Ratte.
LGR6
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
WB: 1:200-1:1000, IHC: 1:20-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
LGR6
(Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
Andere Bezeichnung
LGR6
Hintergrund
Synonyms:FLJ14471, GPCR, LGR6, VTS20631 Background:Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.