LRWD1 Antikörper
Kurzübersicht für LRWD1 Antikörper (ABIN7115828)
Target
Alle LRWD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- LRWD1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- leucine-rich repeats and WD repeat domain containing 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
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Andere Bezeichnung
- LRWD1
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Hintergrund
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Synonyms: Leucine-rich repeat and WD repeat-containing protein 1|Centromere protein 33 (CENP-33)|Origin recognition complex-associated protein (ORC-associated protein, ORCA)|LRWD1|CENP-33|ORCA
Background: Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
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Molekulargewicht
- 85 kDa
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Gen-ID
- 222229
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UniProt
- Q9UFC0
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Pathways
- Chromatin Binding
Target
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