LRRC8D Antikörper

Produktnummer ABIN7115814

Dieses Anti-LRRC8D-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LRRC8D in ELISA und WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für LRRC8D Antikörper (ABIN7115814)

Target: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC8D Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-LRRC8D Antikörper

Verwendungszweck: LRRC8D antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: leucine rich repeat containing 8 family, member D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu LRRC8D

Target: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Andere Bezeichnung: LRRC8D

Hintergrund:

Synonyms: Volume-regulated anion channel subunit LRRC8D|Leucine-rich repeat-containing protein 5|Leucine-rich repeat-containing protein 8D (HsLRRC8D)|LRRC8D|LRRC5

Background: Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition(PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin(PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell(PubMed:24782309).

Molekulargewicht: 98-120 kDa

Gen-ID: 55144

UniProt: Q7L1W4