IREB2 Antikörper

Produktnummer ABIN7115514

Produktdetails anti-IREB2 Antikörper

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IREB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: iron-responsive element binding protein 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu IREB2

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Andere Bezeichnung: IREB2 (IREB2 Produkte)

Hintergrund: Synonyms: Background:RNA-binding protein that binds to iron-responsive elements(IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Molekulargewicht: 90-105 kDa

Gen-ID: 3658

UniProt: P48200

Pathways: Transition Metal Ion Homeostasis