IREB2 Antikörper
Kurzübersicht für IREB2 Antikörper (ABIN7115514)
Target
Alle IREB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- IREB2 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- iron-responsive element binding protein 2
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:2000, IF: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
-
Andere Bezeichnung
- IREB2
-
Hintergrund
-
Synonyms: Iron-responsive element-binding protein 2 (IRE-BP 2)|Iron regulatory protein 2 (IRP2)|IREB2
Background: RNA-binding protein that binds to iron-responsive elements(IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
-
Molekulargewicht
- 90-105 kDa
-
Gen-ID
- 3658
-
UniProt
- P48200
-
Pathways
- Transition Metal Ion Homeostasis
Target
-