Der Kaninchen Polyklonal Anti-IL-10RA-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, IL-10RA in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7115411
Kurzübersicht für IL-10RA Antikörper (ABIN7115411)
Synonyms:IL10R Background:The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.