IFIT3 Antikörper
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- Target Alle IFIT3 Antikörper anzeigen
- IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFIT3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- interferon-induced protein with tetratricopeptide repeats 3
- Isotyp
- IgG
- Top Product
- Discover our top product IFIT3 Primärantikörper
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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (AA 1-490) antibody
IFIT3 Reaktivität: Human WB, ELISA, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) antibodyIFIT3 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (N-Term) antibodyIFIT3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (AA 128-331) antibodyIFIT3 Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (AA 1-490) antibodyIFIT3 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (AA 1-490) antibodyIFIT3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (N-Term) antibodyIFIT3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (AA 51-100) antibodyIFIT3 Reaktivität: Human, Rind (Kuh) WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) antibodyIFIT3 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal 1G1 unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) (C-Term) antibodyIFIT3 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:1000, IP: 1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))
- Andere Bezeichnung
- IFIT3 (IFIT3 Produkte)
- Hintergrund
- Synonyms:CIG-49, IFI60, IFIT4, ISG60 Background:IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27. Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation. IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels. Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21. Can negatively regulate the apoptotic effects of IFIT2.
- Molekulargewicht
- 60 kDa
- Gen-ID
- 3437
- UniProt
- O14879
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