ITGA5 Antikörper

Produktnummer ABIN7115337

Produktdetails anti-ITGA5 Antikörper

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: integrin, alpha 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: Integrin alpha-5 (ITGA5 Produkte)

Synonyme: ITGA5 antikoerper, Cd49e antikoerper, Fnra antikoerper, VLA5 antikoerper, CD49e antikoerper, FNRA antikoerper, VLA5A antikoerper, Itga5_retired antikoerper, integrin subunit alpha 5 antikoerper, integrin alpha 5 (fibronectin receptor alpha) antikoerper, ITGA5 antikoerper, Itga5 antikoerper

Hintergrund: Synonyms:CD49e, FNRA, Integrin alpha 5, Integrin alpha F, ITGA5, VLA 5, VLA5A Background:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).

Molekulargewicht: 120 kDa

UniProt: P08648

Pathways: Integrin Complex