ITGA5 Antikörper
Kurzübersicht für ITGA5 Antikörper (ABIN7115337)
Target
Alle ITGA5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ITGA5 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- integrin, alpha 5
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Andere Bezeichnung
- ITGA5
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Hintergrund
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Synonyms: Integrin alpha-5|CD49 antigen-like family member E|Fibronectin receptor subunit alpha|Integrin alpha-F|VLA-5|Integrin alpha-5 heavy chain|Integrin alpha-5 light chain|ITGA5|FNRA
Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
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Molekulargewicht
- 120 kDa
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UniProt
- P08648
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Pathways
- Integrin Complex
Target
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