IGSF8 Antikörper (AA 28-350)
Kurzübersicht für IGSF8 Antikörper (AA 28-350) (ABIN7115202)
Target
Alle IGSF8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 28-350
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Verwendungszweck
- IGSF8 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 28-350aa
Immunogen: immunoglobulin superfamily, member 8
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
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Andere Bezeichnung
- IGSF8
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Hintergrund
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Synonyms: Immunoglobulin superfamily member 8 (IgSF8)|CD81 partner 3|Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2)|Keratinocytes-associated transmembrane protein 4 (KCT-4)|LIR-D1|Prostaglandin regulatory-like protein (PGRL)|IGSF8|CD81P3|EWI2|KCT4
Background: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 93185
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UniProt
- Q969P0
Target
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