HSD17B11 Antikörper (AA 28-300)

Produktnummer ABIN7115150

Der Kaninchen Polyklonal Anti-HSD17B11-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, HSD17B11 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für HSD17B11 Antikörper (AA 28-300) (ABIN7115150)

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B11 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HSD17B11 Antikörper

Bindungsspezifität: AA 28-300

Verwendungszweck: HSD17B11 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 28-300aa

Immunogen: hydroxysteroid(17-beta) dehydrogenase 11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu HSD17B11

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Andere Bezeichnung: HSD17B11

Hintergrund:

Synonyms: Estradiol 17-beta-dehydrogenase 11|17-beta-hydroxysteroid dehydrogenase 11 (17-beta-HSD 11, 17bHSD11, 17betaHSD11)|17-beta-hydroxysteroid dehydrogenase XI (17-beta-HSD XI, 17betaHSDXI)|Cutaneous T-cell lymphoma-associated antigen HD-CL-03 (CTCL-associated antigen HD-CL-03)|Dehydrogenase/reductase SDR family member 8|Retinal short-chain dehydrogenase/reductase 2 (retSDR2)|Short chain dehydrogenase/reductase family 16C member 2|HSD17B11|DHRS8|PAN1B|SDR16C2

Background: Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Molekulargewicht: 33 kDa

Gen-ID: 51170

UniProt: Q8NBQ5