HARS2 Antikörper

Produktnummer ABIN7115030

Der Kaninchen Polyklonal anti-HARS2 Antikörper wird verwendet zum Nachweis von HARS2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für HARS2 Antikörper (ABIN7115030)

Target: HARS2 (Histidyl-tRNA Synthetase 2, Mitochondrial (Putative) (HARS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HARS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-HARS2 Antikörper

Verwendungszweck: HARS2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: histidyl-tRNA synthetase 2, mitochondrial (putative)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu HARS2

Target: HARS2 (Histidyl-tRNA Synthetase 2, Mitochondrial (Putative) (HARS2))

Andere Bezeichnung: HARS2

Hintergrund:

Synonyms: Histidine--tRNA ligase, mitochondrial|Histidine--tRNA ligase-like|Histidyl-tRNA synthetase (HisRS)|HARS2|HARSL|HARSR|HO3

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.

Molekulargewicht: 50 kDa

Gen-ID: 23438

UniProt: P49590