HNRNPK Antikörper
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- Target Alle HNRNPK Antikörper anzeigen
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HNRNPK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- heterogeneous nuclear ribonucleoprotein K
- Isotyp
- IgG
- Top Product
- Discover our top product HNRNPK Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:10-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Andere Bezeichnung
- HNRNPK (HNRNPK Produkte)
- Synonyme
- CSBP antikoerper, HNRPK antikoerper, TUNP antikoerper, Csbp antikoerper, Hnrpk antikoerper, hnrpk antikoerper, MGC75642 antikoerper, wu:fb37h02 antikoerper, wu:fi34c04 antikoerper, zgc:66162 antikoerper, KBBP antikoerper, NOVA antikoerper, heterogeneous nuclear ribonucleoprotein K antikoerper, heterogeneous nuclear ribonucleoprotein K S homeolog antikoerper, heterogeneous nuclear ribonucleoprotein k antikoerper, HNRNPK antikoerper, Hnrnpk antikoerper, hnrnpk.S antikoerper, hnrnpk antikoerper, LOC5565718 antikoerper, CpipJ_CPIJ000130 antikoerper, NGK_p0004 antikoerper
- Hintergrund
- Synonyms:CSBP, hnRNP K, HNRNPK, HNRPK, TUNP Background:One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction(By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21(lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
- Molekulargewicht
- 51 kDa
- Gen-ID
- 3190
- UniProt
- P61978
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