HLTF Antikörper

Produktnummer ABIN7114924

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HLTF in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für HLTF Antikörper (ABIN7114924)

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HLTF Antikörper

Verwendungszweck: HLTF antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: helicase-like transcription factor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu HLTF

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Andere Bezeichnung: HLTF

Hintergrund:

Synonyms: Helicase-like transcription factor|DNA-binding protein/plasminogen activator inhibitor 1 regulator|HIP116|RING finger protein 80|RING-type E3 ubiquitin transferase HLTF|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3|Sucrose nonfermenting protein 2-like 3|HLTF|HIP116A|RNF80|SMARCA3|SNF2L3|ZBU1

Background: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters(By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair(PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.

Molekulargewicht: 114 kDa

Gen-ID: 6596

UniProt: Q14527