HLTF Antikörper

Produktnummer ABIN7114924

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HLTF in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für HLTF Antikörper (ABIN7114924)

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HLTF Antikörper

Verwendungszweck: HLTF antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: helicase-like transcription factor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu HLTF

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Andere Bezeichnung: HLTF

Hintergrund:

Synonyms: Helicase-like transcription factor|DNA-binding protein/plasminogen activator inhibitor 1 regulator|HIP116|RING finger protein 80|RING-type E3 ubiquitin transferase HLTF|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3|Sucrose nonfermenting protein 2-like 3|HLTF|HIP116A|RNF80|SMARCA3|SNF2L3|ZBU1

Background: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters(By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair(PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.

Molekulargewicht: 114 kDa

Gen-ID: 6596

UniProt: Q14527