HSP70 1A Antikörper (AA 291-641)

Produktnummer ABIN7114899

Dieses Anti-HSP70 1A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HSP70 1A in WB, IHC, ELISA, IP, IF und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HSP70 1A Antikörper (AA 291-641) (ABIN7114899)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSP70 1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-HSP70 1A Antikörper

Bindungsspezifität: AA 291-641

Verwendungszweck: HSPA1A antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 291-641aa

Immunogen: heat shock 70kDa protein 1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000, IP: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Andere Bezeichnung: HSPA1A

Hintergrund:

Synonyms: Heat shock 70 kDa protein 1A|Heat shock 70 kDa protein 1 (HSP70-1, HSP70.1)|HSPA1A|HSP72|HSPA1|HSX70

Background: HSPA1A, collectively known as HSP70(also referred to HSP72), is a stress-inducible member of heat-shock protein 70(HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines.

Molekulargewicht: 66-70 kDa

UniProt: P0DMV8

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process