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H3F3B Antikörper

Dieses Anti-H3F3B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von H3F3B in WB und ELISA. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7114851

Kurzübersicht für H3F3B Antikörper (ABIN7114851)

Target

Alle H3F3B Antikörper anzeigen
H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

Reaktivität

Human, Maus, Ratte

Wirt

  • 7
  • 2
Kaninchen

Klonalität

  • 8
  • 1
Polyklonal

Konjugat

  • 9
Dieser H3F3B Antikörper ist unkonjugiert

Applikation

  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    H3 histone, family 3B(H3.3B)

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

    Andere Bezeichnung

    H3F3B

    Hintergrund

    Synonyms:H3.3B Background:Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Molekulargewicht

    17 kDa

    Gen-ID

    3021

    UniProt

    P84243
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