GNB5 Antikörper

Produktnummer ABIN7114820

Der Kaninchen Polyklonal Anti-GNB5-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet, GNB5 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GNB5 Antikörper (ABIN7114820)

Target: GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-GNB5 Antikörper

Verwendungszweck: GNB5 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: guanine nucleotide binding protein(G protein), beta 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu GNB5

Target: GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))

Andere Bezeichnung: GNB5

Hintergrund:

Synonyms: Guanine nucleotide-binding protein subunit beta-5|Gbeta5|Transducin beta chain 5|GNB5

Background: Heterotrimeric guanine nucleotide-binding proteins(G proteins) function as transducers downstream of G protein-coupled receptors(GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Molekulargewicht: 39-42 kDa

Gen-ID: 10681

UniProt: O14775

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling