GM2A Antikörper (AA 1-193)
Kurzübersicht für GM2A Antikörper (AA 1-193) (ABIN7114727)
Target
Alle GM2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-193
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Verwendungszweck
- GM2A antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-193aa
Immunogen: GM2 ganglioside activator
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Isotyp
- IgG2a
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Applikationshinweise
- WB: 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- GM2A (GM2 Ganglioside Activator (GM2A))
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Andere Bezeichnung
- GM2A
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Hintergrund
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Synonyms: Ganglioside GM2 activator|Cerebroside sulfate activator protein|GM2-AP|Sphingolipid activator protein 3 (SAP-3)|Ganglioside GM2 activator isoform short|GM2A
Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
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Molekulargewicht
- 22 kDa
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Gen-ID
- 2760
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UniProt
- P17900
Target
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