GLYR1 Antikörper
Kurzübersicht für GLYR1 Antikörper (ABIN7114720)
Target
Alle GLYR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- GLYR1 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- cytokine-like nuclear factor n-pac
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
-
Andere Bezeichnung
- GLYR1
-
Hintergrund
-
Synonyms: Cytokine-like nuclear factor N-PAC (NPAC)|3-hydroxyisobutyrate dehydrogenase-like protein|Glyoxylate reductase 1 homolog|Nuclear protein NP60|Nuclear protein of 60 kDa|Nucleosome-destabilizing factor (hNDF)|Putative oxidoreductase GLYR1|GLYR1|HIBDL|NDF|NP60|NPAC
Background: May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3(H3K36me3).
-
Molekulargewicht
- 60 kDa
-
Gen-ID
- 84656
-
UniProt
- Q49A26
Target
-