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Glutaredoxin 2 Antikörper

GRX2 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7114635
  • Target Alle Glutaredoxin 2 (GRX2) Antikörper anzeigen
    Glutaredoxin 2 (GRX2)
    Reaktivität
    • 40
    • 22
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 34
    • 6
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glutaredoxin 2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 21
    • 13
    • 13
    • 9
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    glutaredoxin 2
    Isotyp
    IgG
    Top Product
    Discover our top product GRX2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    Glutaredoxin 2 (GRX2)
    Andere Bezeichnung
    GLRX2 (GRX2 Produkte)
    Synonyme
    ECK1049 antikoerper, JW1051 antikoerper, CGI-133 antikoerper, GRX2 antikoerper, 1700010P22Rik antikoerper, AI645710 antikoerper, Grx2 antikoerper, glutaredoxin 2 (Grx2) antikoerper, glutaredoxin Grx2 antikoerper, thioredoxin antikoerper, glutaredoxin 2 antikoerper, glutaredoxin 2 (thioltransferase) antikoerper, grxB antikoerper, grx2 antikoerper, AF_RS10790 antikoerper, GLRX2 antikoerper, Glrx2 antikoerper
    Hintergrund
    Synonyms:GRX2 Background:Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
    Molekulargewicht
    16 kDa
    Gen-ID
    51022
    UniProt
    Q9NS18
    Pathways
    Cell RedoxHomeostasis
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