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Glutaredoxin 2 Antikörper

Dieses Anti-Glutaredoxin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Glutaredoxin 2 in WB und ELISA. Geeignet für Human, Ratte und Maus.
Produktnummer ABIN7114635

Kurzübersicht für Glutaredoxin 2 Antikörper (ABIN7114635)

Target

Alle Glutaredoxin 2 (GRX2) Antikörper anzeigen
Glutaredoxin 2 (GRX2)

Reaktivität

  • 48
  • 22
  • 8
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Ratte, Maus

Wirt

  • 42
  • 6
Kaninchen

Klonalität

  • 46
  • 2
Polyklonal

Konjugat

  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glutaredoxin 2 Antikörper ist unkonjugiert

Applikation

  • 34
  • 22
  • 13
  • 13
  • 11
  • 10
  • 8
  • 7
  • 6
  • 3
  • 3
  • 2
Western Blotting (WB), ELISA
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    glutaredoxin 2

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    Glutaredoxin 2 (GRX2)

    Andere Bezeichnung

    GLRX2

    Hintergrund

    Synonyms:GRX2 Background:Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

    Molekulargewicht

    16 kDa

    Gen-ID

    51022

    UniProt

    Q9NS18

    Pathways

    Cell RedoxHomeostasis
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