GOT1 Antikörper (AA 1-413)

Produktnummer ABIN7114620

Dieser Anti-GOT1-Antikörper ist ein Maus-Monoklonal-Antikörper zum Nachweis von GOT1 in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für GOT1 Antikörper (AA 1-413) (ABIN7114620)

Target: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GOT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 2F1

Produktdetails anti-GOT1 Antikörper

Bindungsspezifität: AA 1-413

Verwendungszweck: GOT1 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-413aa

Immunogen: glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu GOT1

Target: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Andere Bezeichnung: GOT1

Hintergrund:

Synonyms: Aspartate aminotransferase, cytoplasmic (cAspAT)|Cysteine aminotransferase, cytoplasmic|Cysteine transaminase, cytoplasmic (cCAT)|Glutamate oxaloacetate transaminase 1|Transaminase A|GOT1

Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Molekulargewicht: 43 kDa

Gen-ID: 2805

UniProt: P17174

Pathways: Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process