GPSM1 Antikörper

Produktnummer ABIN7114427

Der Kaninchen Polyklonal Anti-GPSM1-Antikörper wurde für ELISA, WB, IHC und IF validiert. Er ist geeignet, GPSM1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GPSM1 Antikörper (ABIN7114427)

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPSM1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GPSM1 Antikörper

Verwendungszweck: GPSM1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: G-protein signaling modulator 1(AGS3-like, C. elegans)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu GPSM1

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Andere Bezeichnung: GPSM1

Hintergrund:

Synonyms: G-protein-signaling modulator 1|Activator of G-protein signaling 3|GPSM1|AGS3

Background: GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).

Molekulargewicht: 72 kDa

Gen-ID: 26086

UniProt: Q86YR5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling